文章摘要
基于数据挖掘探讨李吉彦教授治疗慢性萎缩性胃炎的经验
投稿时间:2026-06-17  修订日期:2026-06-18
DOI:
中文关键词: 数据挖掘  李吉彦  萎缩性胃炎  用药规律
英文关键词: Data mining  Li Jiyan  Atrophic gastritis  Medication rule
基金项目:辽宁省“兴辽英才”医学名家项目(项目编号:YXMJ-QNMZY-19)
作者单位邮编
张洋* 大连医科大学附属第二医院 116000
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中文摘要:
  目的 运用数据挖掘技术分析李吉彦教授治疗慢性萎缩性胃炎(CAG)的用药规律,总结其辨治经验。方法 收集2025年4月至2026年4月李吉彦教授门诊治疗CAG的232份病历,建立数据库,通过古今医案云平台进行中药频次、性味归经、关联规则、复杂网络及聚类分析。结果 232例CAG患者以50~69岁为高发年龄段,女性略多于男性;证型以气滞浊瘀证(40.95%)最多见,其次为寒热浊瘀证(25.00%),各证型均以“浊瘀”为共同病理基础。使用频次最高的中药为土茯苓(93.10%)、太子参(90.95%)、木香(89.66%)、海螵蛸(85.34%)、连翘(84.91%)等;药性以温、平为主,药味以甘、苦、辛为主,归经以脾、肺、肝、胃经居多。关联规则与复杂网络分析显示,核心药物组合为土茯苓、太子参、木香,形成“益气健脾—理气化浊—解毒除湿”的核心架构。聚类分析将高频药物归纳为健脾益气、补益肝肾、辛开苦降、核心处方、随证加减、安神定志6个模块。结论 李吉彦教授治疗CAG以从“滞”论治、化浊祛瘀为特色,核心处方以益气健脾固本、理气化浊治标,用药平和,结构清晰,体现了辨病与辨证相结合的学术思想。
英文摘要:
    Objective? To analyze the medication patterns of Professor Li Jiyan in the treatment of chronic atrophic gastritis (CAG) using data mining techniques, and to summarize his clinical experience.Methods? A total of 232 medical records of CAG patients treated by Professor Li Jiyan in the outpatient clinic from April 2025 to April 2026 were collected to establish a database. The Ancient and Modern Medical Records Cloud Platform was used to conduct frequency analysis of Chinese herbs, analysis of nature, flavor and meridian tropism, association rule analysis, complex network analysis, and cluster analysis. Results? Among the 232 CAG patients, the peak age of onset was 50–69 years, with females slightly outnumbering males. The most common syndrome was qi stagnation and turbid stasis syndrome (40.95%), followed by cold-heat and turbid stasis syndrome (25.00%), and all syndromes shared “turbidity and stasis” as the common pathological basis. The most frequently used herbs were Smilax glabra (93.10%), Radix Pseudostellariae (90.95%), Aucklandia lappa (89.66%), Endoconcha Sepiae (85.34%), and Forsythia suspensa (84.91%). The medicinal properties were predominantly warm and neutral; the flavors were mainly sweet, bitter, and acrid; and the meridian tropism chiefly focused on the spleen, lung, liver, and stomach meridians. Association rule and complex network analyses revealed a core herbal combination consisting of Smilax glabra, Radix Pseudostellariae, and Aucklandia lappa, forming a central framework of “supplementing qi and invigorating the spleen — regulating qi and resolving turbidity — detoxifying and draining dampness.”
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