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| 滋肾育胎丸联合阿托西班治疗晚期先兆流产的临床疗效观察 |
| The Efficacy of Zishen Yutai Pills Combined with Atosiban in the Treatment of Late Threatened Abortion |
| 投稿时间：2026-10-16 修订日期：2026-10-16 |
| DOI： |
中文关键词: 滋肾育胎丸 阿托西班 晚期先兆流产 |
| 英文关键词: Zishen Yutai Pills Atosiban Late threatened abortion |
| 基金项目: |
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| 摘要点击次数: 80 |
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| 中文摘要: |
:目的:观察滋肾育胎丸联合阿托西班治疗晚期先兆流产的临床疗效。方法:纳入2024年1月至2025年6月在唐山市妇幼保健院产科收治的80例晚期先兆流产患者作为研究对象,所有患者均符合晚期先兆流产临床诊断标准,且自愿参与本次研究。采用随机数字表法将研究对象分为对照组与联合治疗组,每组各40例。对照组患者单纯采用醋酸阿托西班注射液进行常规保胎治疗；联合治疗组在对照组西药治疗的基础上,联合口服滋肾育胎丸辅助治疗,滋肾育胎丸服用至症状消失为止。治疗期间密切观察患者病情变化,重点对比分析两组患者各项临床症状的持续时间。结果:临床观察结果显示,相比对照组,联合治疗组患者的宫缩(0 d vs. 3 d)、腹部疼痛(0 d vs. 3 d)、下腹坠胀不适(0 d vs. 3 d)持续时间的中位数均显著短于单纯西药治疗的对照组(P均<0.05)。两组患者阴道出血症状持续时间的中位数(2 d vs. 1 d)差异无统计学意义(P=0.814)。结论:针对晚期先兆流产患者,与单用醋酸阿托西班注射液相比,联合滋肾育胎丸治疗可显著缩短宫缩、腹痛及下腹坠胀症状的持续时间。 |
| 英文摘要: |
| Objective: To observe the clinical efficacy of Zishen Yutai Pills combined with atosiban in the treatment of late threatened abortion.Methods: A total of 80 patients with late threatened abortion admitted to the Department of Obstetrics, Tangshan Maternity and Child Health Hospital between January 2024 and June 2025 were enrolled. All patients satisfied the clinical diagnostic criteria for late threatened abortion and provided voluntary informed consent for the study. Participants were randomized by the random number table method into control group and combination group, 40 patients per group. The control group received atosiban acetate injection for routine fetal protection. The combination group received oral Zishen Yutai Pills as adjuvant therapy on top of atosiban acetate injection. ZYP was continued until symptom resolution. Clinical status was closely followed during treatment. The duration of clinical symptoms was compared between groups.Results: Clinical observations showed that the median durations of uterine contraction (0 d vs. 3 d), abdominal pain (0 d vs. 3 d), and lower abdominal distension and discomfort in the combination treatment group were significantly shorter than those in the control group receiving western medicine alone (all P < 0.05). There was no statistically significant difference in the median duration of vaginal bleeding between the two groups (2 d vs. 1 d) (P = 0.814).Conclusion: patients with late threatened abortion, combination therapy of Zishen Yutai Pills and atosiban acetate injection significantly shortens the duration of uterine contractions, abdominal pain and lower abdominal distension compared with atosiban acetate injection monotherapy. |
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