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Fund Project:武汉市青年科技晨光计划课题（No.2017050304010279）； 湖北省卫生计生委课题（No.20172026）； 华中科技大学自主创新基金青年教师基金（No.2015QN203）； 协和医院自由创新预研基金（No.201762）
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