| Objective To observe the clinical efficacy of Dingchuan Huatan Decoction combined with acupoint application in the treatment of bronchial asthma with the syndrome of cold-fluid retained in the lung, and its effects on pulmonary function and inflammatory factor levels. Methods Sixty-six patients with bronchial asthma of the cold-fluid retained in the lung syndrome were randomly divided into a control group and a treatment group, with 33 cases in each group. The control group received conventional Western medicine treatment, while the treatment group was additionally treated with Dingchuan Huatan Decoction combined with acupoint application on the basis of the control treatment for 8 weeks. A total of 62 patients completed the study, including 32 in the control group and 30 in the treatment group. Pulmonary function, serum levels of IL-4, IL-5, IFN-γ, and IgE, traditional Chinese medicine syndrome scores, ACT scores, and adverse reactions were compared between the two groups before and after treatment. Results After treatment, pulmonary function in both groups was improved compared with that before treatment, and the improvement in the treatment group was superior to that in the control group. Serum IL-4, IL-5, and IgE levels decreased in both groups, with greater reductions in the treatment group. IFN-γ increased in the treatment group, whereas no corresponding improvement was observed in the control group. TCM syndrome scores decreased and ACT scores increased in both groups, with greater improvement in the treatment group. The total effective rate in the treatment group was higher than that in the control group, but the difference was not statistically significant (P>0.05). No serious adverse reactions were observed in either group. Conclusion Dingchuan Huatan Decoction combined with acupoint application can improve pulmonary function, inflammatory factor levels, and clinical symptoms in patients with bronchial asthma of the cold-fluid retained in the lung syndrome, with good safety. |